VEGF - A secretion in human gastric cancer : clinicopathological correlations and therapeutical implications
نویسندگان
چکیده
Olivia Crociani*, Elena Lastraioli*, Luca Boni*, Serena Pillozzi, Maria Raffaella Romoli, Massimo D’Amico, Matteo Stefanini Silvia Crescioli, Antonio Taddei, Lapo Bencini, Marco Bernini, Marco Farsi, Stefania Beghelli , Aldo Scarpa, Luca Messerini, Anna Tomezzoli, Carla Vindigni, Paolo Morgagni, Luca Saragoni, Elisa Giommoni, Silvia Gasperoni, Francesco Di Costanzo, Franco Roviello, Giovanni De Manzoni , Paolo Bechi and Annarosa Arcangeli
منابع مشابه
Human Cancer Biology hERG1 Channels Regulate VEGF-A Secretion in Human Gastric Cancer: Clinicopathological Correlations and Therapeutical Implications
Purpose: hERG1 channels are aberrantly expressed in several types of human cancers, where they affect different aspects of cancer cell behavior. A thorough analysis of the functional role and clinical significance of hERG1 channels in gastric cancer is still lacking. Experimental Design: hERG1 expression was tested in a wide (508 samples) Italian cohort of surgically resected patients with gast...
متن کاملhERG1 channels regulate VEGF-A secretion in human gastric cancer: clinicopathological correlations and therapeutical implications.
PURPOSE hERG1 channels are aberrantly expressed in several types of human cancers, where they affect different aspects of cancer cell behavior. A thorough analysis of the functional role and clinical significance of hERG1 channels in gastric cancer is still lacking. EXPERIMENTAL DESIGN hERG1 expression was tested in a wide (508 samples) Italian cohort of surgically resected patients with gast...
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Gastric cancer is one of the most common cancers in the world. Late diagnosis is the main cause of the high rate of treatment failure and death among patients with gastric cancer; therefore identifying the molecular basis of cancer initiation and metastasis is so critical for developing efficient methods for early diagnosis and therapy. long non-coding RNAs (lncRNAs) are the largest group of no...
متن کاملPrognostic Effect of Vascular Endothelial Growth Factor and Angiogenesis in Gastric Carcinoma.
PURPOSE Many studies have shown that angiogenesis has an important role in the growth, progression, and metastasis of solid tumors. Recently, several angiogenic factors have been identified. Vascular endothelial growth factor (VEGF) is a well characterized inducer of angiogenesis. In this study, we investigated the prognostic significance of the expression of VEGF in patients with an advanced g...
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Background: Extracellular matrix protein 1 (ECM1) and vascular endothelial growth factor-C (VEGF-C) are secretory glycoproteins which that are highly associated the with lymphangiogenesis; and thus maythese proteins could, therefore, play important part roles in the lymphatic dissemination of tumors. However, their roles are stillvery little is known about their potential roles in lymphangiogen...
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